As a Woman

Fertility Q&A: Miscarriage, Low AMH, PCOS & More

Mar 2, 2026
Listeners hear clear explanations of Turner mosaicism and when IVF with genetic testing might be considered. Timing and interpretation of LH/FSH ratios and how they relate to PCOS come up. Very low AMH at a young age prompts discussion of repeat testing, scans, and fertility preservation. Effects of CBD/THC on sperm and strategies for same-sex IUI with possible endometriosis are also covered.
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ADVICE

Consider IVF With PGT For Turner Mosaicism

  • Consider IVF with PGT when Turner mosaicism and recurrent miscarriages are present.
  • Test ovarian reserve (AMH) and discuss family size and urgency because Turner mosaic can cause early ovarian failure.
INSIGHT

LH/FSH Ratio Needs Cycle Day Context

  • LH and FSH must be interpreted by cycle day and alongside estradiol and AMH for meaningful conclusions.
  • Mid-cycle LH spikes are normal, so an elevated LH/FSH ratio near ovulation doesn't reliably indicate PCOS.
ADVICE

Verify Extremely Low AMH With Ultrasound Or Repeat Test

  • Repeat a very low AMH or correlate it with an antral follicle count before making big decisions.
  • Labs can be wrong; get an ultrasound and possibly a repeat AMH to confirm true ovarian reserve.
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