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Start DKA Treatment with Fluids
- Prioritize fluid resuscitation as the initial treatment in DKA with 15-20 mL/kg or 1-1.5 L in the first hour.
- This restores organ perfusion before initiating insulin therapy.
Balanced Fluids Benefit DKA Patients
- Balanced fluids improve time to DKA resolution compared to normal saline by reducing chloride load.
- Using balanced fluids is supported by multiple studies including a meta-analysis.
Tailor Insulin Infusion to Patient
- Use titratable insulin infusions for patients at higher hypoglycemia risk or with euglycemic DKA.
- Adjust insulin and dextrose infusions based on glucose levels to balance glucose control and hypoglycemia prevention.


