Solving Medical Mysteries—and the Diagnosis Crisis (Alexandra Sifferlin)

Alexandra Sifferlin's 'The Elusive Body' investigates the widespread problem of diagnostic errors, combining patient stories, interviews with clinicians, and reporting on systemic problems. The book examines how advances in medical technology have improved diagnosis for many but left others underserved, and profiles networks and clinicians working to solve hard-to-diagnose cases. Sifferlin highlights the emotional and practical consequences for patients who endure diagnostic odysseys and the ways health systems often fail to provide feedback to clinicians. She also explores conditions like long COVID and rare genetic disorders to illustrate challenges across organ-based medicine and systemic illnesses. Throughout, the book advocates for better feedback, multidisciplinary approaches, and patient involvement to reduce diagnostic harm.