
The Joe Rogan Experience #672 - Dr. Rhonda Patrick
Jul 21, 2015
Dr. Rhonda Patrick, a Ph.D. biomedical scientist and founder of FoundMyFitness, dives into fascinating health topics. She discusses how sauna use can dramatically lower mortality rates and explains the benefits of hyperbaric oxygen therapy, as well as its risks. Rhonda also explores the value of cold exposure for synapse regrowth and the role of lactate as fuel for the brain. Additionally, she shares insights on personalized nutrition based on genetic variations and highlights the impact of vitamin D on serotonin and impulse control.
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Use Cold Therapy Based On Training Context
- Use cold therapy contextually: apply cryo/cold immersion to reduce excessive inflammation after very strenuous training.
- Avoid routine cold immediately after light workouts if hypertrophy is your goal, because it can blunt growth signals.
Cold Exposure Robustly Raises Norepinephrine
- Whole-body cold or immersion triggers a robust 2–3x increase in norepinephrine that persists across repeated sessions.
- Norepinephrine improves attention, mood, analgesia, and reduces inflammation centrally and peripherally.
Biological Age Diverges Widely By Your 30s
- Biological aging diverges strongly by mid-30s: people same age showed cellular ages ±10 years.
- Physical appearance correlated with measured biological age, linking lifestyle to cellular aging.

