JACC This Week November 4, 2025: The 2025 Hypertension Guideline: A New Era in Blood Pressure Control | JACC This Week
Oct 28, 2025
Discover the groundbreaking 2025 hypertension guidelines that aim to shift blood pressure control into a new era. Key updates include lower blood pressure targets and the importance of out-of-office monitoring. Delve into the role of technology in hypertension care, promoting team-based strategies for better patient outcomes. Contributing experts discuss innovative approaches like single-pill combinations and the need for a cultural change in addressing severe hypertension. Explore practical strategies and next steps to make uncontrolled hypertension a 'never event'.
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Lower Targets Reaffirmed And Broadened
- The 2025 HA-ACC guideline reaffirms treating to systolic BP <130 mmHg and encourages <120 mmHg when feasible.
- It integrates out-of-office monitoring, team-based care, and cardio-kidney-metabolic framing to push implementation beyond publication.
Adopt Out-Of-Office Monitoring
- Use home and ambulatory blood pressure monitoring for diagnosis and management rather than relying only on office readings.
- Start most patients needing medication on single-pill combination therapy to improve adherence and control.
Make Severe Hypertension A Never Event
- Severe hypertension (systolic >160 mmHg) should be treated as a systems-level preventable failure.
- Krumholz proposes making uncontrolled severe hypertension a 'never event' through infrastructure and accountability.