Extracellular Vesicles Vantage Point – Andreas Baur, Fairmont State University, College of Science & Technology – The Role of Extracellular Vesicles

Andreas Baur, of the College of Science & Technology at Fairmont State University, talks in detail about his interesting research studying extracellular vesicles (EVs).

Podcast Points:

• What is the role of extracellular vesicles in the progression of neurodegenerative disease and cancer?
• What is protease?
• Looking at enzymatic activity. What can be learned?

Dr. Baur earned his doctorate in organic chemistry from the University of Regensburg before settling into his current duties, and lab work, at Fairmont State. Dr. Baur talks about his research, past, and present. Some of his current work in the lab focuses on the systematic analyzation of vesicles in patients (in plasma). And as a medical doctor, Baur has the kind of access to patients that is necessary for this work.

Dr. Baur discusses his past work studying HIV and proteins, considering in vitro studies and the pivotal role of vesicles. He discusses his curiosity, and the questions about why certain proteases were found within, why are certain vesicles in plasma, and why are there even more in HIV, that drove him to dig deeper into his research to find the answers.

The research investigator and medical doctor talks about various types of cancers, discussing relapse factors, select patterns, and the continuing role of vesicles. Dr. Baur explains how they use purified vesicles for two types of important diagnostic tests—measuring enzymatic activity as well as looking at proteases, and also in the analysis of factors found in these vesicles.

Wrapping up, Dr. Baur discusses coronavirus, transmission, and disease conditions. He talks in-depth about neurodegenerative diseases, other types of diseases, and the various connections, pertaining to vesicles.