Food Matters Live Podcast 592: Bridging the cognitive health nutrient gap
Jan 12, 2026
Dr. Anniko Korozi, Associate Professor at the University of Amsterdam studying early life adversity, neuroimmune mechanisms and nutritional interventions. She discusses how early nutrients like omega-3s and choline may protect lifelong cognition. Short talks cover microglia, maternal milk as a transfer route, and promising botanicals such as spearmint and curcumin.
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Effective Omega-3 Doses Exceed Guidelines
- Trial evidence for cognitive benefits typically uses ≥900 mg EPA+DHA, higher than food guideline recommendations of 250–500 mg.
- Sophie contrasted RCT doses (up to grams) with lower dietary/supplement averages to show a clear discrepancy.
Choline Is Missing From Most Brain Supplements
- Choline is underappreciated, scarce in common diets, and often absent from top-selling brain supplements.
- Sophie pointed out eggs and beef liver as primary sources and found none of Amazon's 10 best-selling brain supplements contained choline.
Polyphenols Offer Multiple Cognitive Mechanisms
- Botanicals rich in polyphenols show emerging evidence for cognitive domains via antioxidant, anti-inflammatory, vascular and signaling effects.
- Sophie described polyphenols from herbs, fruits and wine acting on blood flow, oxidative stress and neuroprotection.