GOTO - The Brightest Minds in Tech Clean Architecture with Python • Sam Keen & Max Kirchoff
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Feb 13, 2026 
Sam Keen, founder and researcher and author of Clean Architecture with Python, brings 30 years of software and architecture experience. He discusses pragmatic Pythonic adaptations of clean architecture. They cover dependency management, onion-layer structure, testability as an architecture health signal, when to wrap third-party services, and how layered design works with AI-assisted development.
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Focus On Thoughtful Dependency Management
- Clean architecture centers on managing dependencies thoughtfully to avoid long-term 'dependency hell'.
- Sam Keen frames clean as adaptable principles, not a rigid framework for Python developers.
Stick To Pythonic Tools And Pragmatism
- Use Python-native tools like typing, protocols, and ABCs to keep designs Pythonic.
- Thin down principles to your context instead of blindly applying every pattern.
Strict Inside, Flexible Outside
- The onion (bullseye) model enforces inward-only dependencies and isolates domain logic.
- Focus first on internal domain and application layers; adapter/framework layers are more context-specific.
