Conan O’Brien Needs A Friend David Sedaris
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Feb 4, 2019 
Writer and humorist David Sedaris talks about the perks of having a colonoscopy, backhanded compliments, being honest about your family, and how to dispose of old tumors. Conan and his assistant respond to a listener voicemail regarding a wax museum conspiracy.
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Uncomfortable Medical Procedures Turn Comic
- David Sedaris described a urinary investigation where doctors inserted a camera and referenced his sphincter with a Scottish doctor.
- Conan and Sedaris compared colonoscopy drugs, calling them euphoric and habit-forming.
Colonoscopy Drug Described As Religious Bliss
- Conan and David rhapsodized about the sedative used for colonoscopies, calling it a religious or 'cloud of love' experience.
- They joked about doing dual colonoscopies and the drug's addictive afterglow.
How Sedaris Reads His Audience On Tour
- Sedaris described book tour routines: signing books before shows to gauge audiences and preferring brief fan interactions.
- He admits he's not good at long friendships and uses short Q&A exchanges to connect.