Critical Matters

Acute Ischemic Stroke

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Sep 15, 2022
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ADVICE

Medical Steps Before Hemicraniectomy

  • Prevent and treat malignant edema with BP and glucose control, hyperosmolar therapy, and consider glibenclamide trials.
  • Use hypertonic saline to target serum sodium ~150–155 mmol/L in selected patients.
INSIGHT

Recanalization Lowers Craniectomy Need

  • Early hemicraniectomy saves lives in younger patients but often leaves significant disability.
  • Recanalization reduces the need for hemicraniectomy by preventing large-core infarcts.
ADVICE

Control BP And Glucose Post-Reperfusion

  • Monitor for hemorrhagic transformation after reperfusion and control BP and glucose to reduce risk.
  • Tailor post-reperfusion BP: <180 mmHg after tPA, lower (≈140) after good recanalization.
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