No Priors: Artificial Intelligence | Technology | Startups

AI for Atoms: How Periodic Labs is Revolutionizing Materials Engineering with Co-Founder Liam Fedus

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Apr 3, 2026
Liam Fedus, former Google Brain and OpenAI researcher and co-founder of Periodic Labs, explores using AI to engineer materials at the atomic level. He talks about moving from ChatGPT to atoms, fixing data scarcity in materials science, using language models to coordinate specialized neural nets, and why robotics, AGI, and lab automation could reshape physical innovation.
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ANECDOTE

How Liam Fedus Went From Physics to Frontier AI

  • Liam Fedus moved from dark matter physics into AI after gravitating toward machine learning problems in grad school.
  • At Google Brain in 2016 to 2017, he worked amid early distributed training, mixture of experts, and transformer breakthroughs.
ANECDOTE

Why OpenAI Chose a General Chatbot

  • At OpenAI, Liam Fedus helped turn GPT-4 into a product by backing John Schulman's push for a general chatbot.
  • He said ideas like meeting bots felt less compelling, and ChatGPT became the effort that launched broad public awareness.
INSIGHT

Why Materials AI Needs Experimental Ground Truth

  • Materials AI needs more than literature because reported properties can vary by orders of magnitude and never reach ground truth.
  • Periodic uses closed-loop experiments to generate data, inspect aberrations, compare with simulations, and choose the next experiments.
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