Short Wave

Solving The Sleep & Alzheimer's Puzzle

Nov 21, 2019
Jon Hamilton, an NPR science correspondent and expert on brain science and sleep research, dives into the intriguing connection between sleep and Alzheimer's disease. He shares insights from researchers who explore how poor sleep might increase the risk of developing Alzheimer's. The discussion highlights groundbreaking studies revealing the brain's detoxification processes during deep sleep and the critical role it plays in safeguarding brain health. This captivating talk unveils the powerful link between restful nights and cognitive wellness.
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INSIGHT

Alzheimer's & Sleep Connection

  • People with Alzheimer's experience sleep problems like nighttime wakefulness and daytime drowsiness.
  • Scientists are investigating if sleep problems contribute to the onset of Alzheimer's.
INSIGHT

Brain's Dishwasher

  • During sleep, brain cells shrink, allowing cerebrospinal fluid (CSF) to flow through the brain, washing out toxins.
  • This "glymphatic system" uses blood vessels as a scaffold for CSF to exchange with brain fluid.
INSIGHT

Beta-Amyloid and Sleep

  • Beta-amyloid, a waste product linked to Alzheimer's, builds up in the brain.
  • Lack of sleep may accelerate the formation of beta-amyloid plaques, potentially increasing Alzheimer's risk.
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