
The Rest Repair Recover Podcast ADHD, Chronic Illness & The Hidden Link: Doctor Reveals Surprising Truths!
Jun 2, 2025
In this insightful discussion, Dr. James Kustow, a consultant psychiatrist specializing in adult ADHD, uncovers the surprising connections between ADHD, chronic illness, and immune system function. He explores the impact of mast cells on both mental health and inflammation, providing practical strategies for self-care. The conversation delves into the unique challenges of diagnosing ADHD in adults and women, especially during hormonal changes. Dr. Kustow emphasizes the importance of a holistic approach to treatment, enhancing our understanding of these intertwined health issues.
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Triad Drives Chronic Symptoms
- The triad of hypermobility, mast cell activation, and dysautonomia explains many chronic symptoms.
- Blood vessel laxity causes poor brain perfusion impacting mental clarity and fatigue.
Mast Cell Role in Immunity
- Mast cells guard environmental interfaces and trigger inflammatory and repair responses.
- Their overactivation leads to multisystem symptoms linked to allergies, pain, and swelling.
Long COVID and Mast Cells
- Long COVID exemplifies mast cell hyperreactivity causing persistent inflammation and tissue remodeling.
- Proper inflammation timing and resolution are crucial to healing and symptom reduction.



