Hormone Optimization: Testosterone, HRT, Hair Loss & Obesity with Dr. Kyle Gillett, MD

In this rebroadcast of the original conversation from earlier this year, Dr. Kyle Gillett and Dr. Stephanie embark on a deep dive into the intricate world of hormones, with a special focus on androgens. During the conversation they touch on the critical role of sleep, discuss the complexities of PCOS, and delve into the mysteries of hair and hair loss. They also explore TRT, or testosterone replacement therapy, and the broader spectrum of hormonal replacement therapy for women.

Dr. Kyle also shares his knowledge in the realm of obesity, exploring the neurobiology and genetic foundations that contribute to this complex issue. So, get ready for a journey through the lipostat and ventromedial hypothalamus—yes, all the geeky things that Dr. Stephanie loves to dissect.

Connect with Dr. Kyle on:
IG - https://www.instagram.com/kylegillettmd/
Website - https://gilletthealth.com/
Podcast - https://podcasts.apple.com/ca/podcast/the-gillett-health-podcast/id1631735999
YouTube - https://www.youtube.com/@gilletthealth6738/videos
IG - https://www.instagram.com/gilletthealth/

Resources Mentioned:
Gorilla Mind - https://gorillamind.com

Episode Overview:

00:00:00 Introduction

00:02:48 Welcome to Dr. Kyle Gillett and the Topic of Hormones

00:12:02 The Best Diet: Omnivorous or Plant-Based?

00:22:03 Differential Conversion of Testosterone to DHT in Various Cells

00:24:31 PCOS and Androgen Dominance

00:30:53 Optimizing DHT Levels in the Body

00:32:04 Creatine and Its Impact on DHT Levels

00:33:45 Extending Fertility in Women and the Role of HRT

00:36:58 The Importance of Maintaining a High-Performing Body

00:42:35 L-Carnitine: An Option for Plant-Based Diets

00:46:39 Boron and Its Role in Hormone Optimization

00:50:06 Half-life of SHBG and Its Regulation

00:53:26 Hair Loss and the Different Types of Hair Loss Explained

01:02:17 Practices for Improving Sleep and Hormone Optimization

01:06:21 The Connection Between Sleep, Menopause, and Estrogen Reduction

01:07:59 The Complexity of Obesity and Calorie Balance

01:13:05 Importance of Maintaining Lean Body Mass During Weight Loss

01:16:17 Strategies to Circumvent Feedback Mechanisms for Weight Loss

01:20:43 Strategies to Slow Down Eating and Practice Intuitive Eating

01:29:14 Leptin and Its Role in Satiety and Fat Mass

01:35:31 Why Don't All of Us Become Obese? Genetic Factors

01:38:33 Testosterone, Dopamine, and Palatability of Foods

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P.S. When you're ready, here are two ways Dr. Stephanie can help you:

Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.

Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results.

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