The Rest Is Science How Evolution Is Shaping Cancer Research
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Mar 26, 2026 A tour of how cancer behaves like a fast‑evolving ecosystem and what that means for new therapies. They highlight mapping tumor evolution and targeting durable mutations. Listeners hear about neoantigen detection and early‑stage vaccine ideas. The conversation covers animal cancer resistance, unusual whale studies, extrachromosomal DNA, viral fossils and novel immune and viral delivery strategies.
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Target Neoantigen Red Flags Early
- Use early neoantigen signals as detection and prevention targets rather than waiting for visible tumours.
- LungVax trains the immune system to recognise neoantigen 'red flags' on pre-cancerous lung cells to prevent cancer developing.
Centenarians Offer Clues To Cancer Resistance
- Studying 'super avoiders' like centenarians can reveal protective immune histories and antibodies.
- Team Atlas will build a cancer antibody atlas to find autoantibodies correlated with long cancer-free lifespans.
How Scientists Sample Whale Biology At Sea
- Researchers collect whale data with sniffer dogs and drone-mounted cups to sample blowhole aerosols and study whale biology noninvasively.
- They also age whales by counting rings in long earwax plugs to link longevity and cancer incidence.