Short Wave

Could this vaccine trial mean a future without HIV?

19 snips
Feb 16, 2026
Ari Daniel, a freelance science reporter who covered an innovative Pan-Africa HIV vaccine trial, shares field reporting from South Africa and Zanzibar. He describes lab work with long-term blood samples. He recounts a funding freeze that threatened the trial and how researchers regrouped with new, smaller funding. He follows the launch of the scaled-back trial and community reactions in Cape Town.
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ANECDOTE

Decades Of Donated Samples

  • Penny Moore describes a freezer room holding decades of samples from 117 South African women who donated blood for HIV research.
  • Those samples have enabled deep study of how HIV evolves and informed work on other diseases like COVID-19.
ANECDOTE

Funding Halted In Zanzibar

  • At a Zanzibar meeting, USAID funding froze after an executive order, stopping a $45 million HIV vaccine program just before it began.
  • Penny Moore and colleagues received stop-work orders and watched months of planning collapse overnight.
ADVICE

Raise Backup Funding Quickly

  • When large grants collapse, pursue diverse funding sources quickly and write emergency proposals.
  • Penny's team secured smaller local and philanthropic grants to keep the trial alive, albeit scaled back.
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