Doctor Eye Health Podcast

When Dry Eye Turns Into Chronic Eye Pain - Expert Discussion

6 snips
Feb 18, 2026
Dr. Jacqueline Theis, a neuro‑optometrist focused on brain injury and neurosensory dysfunction, and Dr. Laura Periman, a cornea specialist concentrating on inflammation-driven dry eye and neuropathic corneal conditions, discuss how dry eye can evolve into chronic ocular pain. They cover trigeminal nerve links to the brain, neurotrophic keratitis versus neuropathic pain, diagnostic tests, and multidisciplinary treatment approaches.
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INSIGHT

Trigeminal Pathway Connects Eye Blink Tear And Neck

  • The trigeminal nerve links corneal sensation, blink, and tear production through a multi-neuron pathway that includes neck inputs.
  • Disruption anywhere from the cornea to the brain (and neck) can alter blinking and tear control.
ADVICE

Test Corneal Sensation And Blink Rate Quantitatively

  • Measure corneal sensation and blink mechanics, not just surface dyes; use tools like Cochet-Bonnet or Schirmer and count basal blink rate for diagnostics.
  • Laura Periman quantifies sensation and tracks response to therapy rather than relying on crude cotton wisp tests.
INSIGHT

Inflammation And Nerve Damage Create A Vicious Pain Loop

  • Chronic surface inflammation can damage corneal nerve receptors causing hyperalgesia and allodynia where mild stimuli produce severe pain.
  • Damaged nerves then trigger inflammation in a self-amplifying loop that perpetuates symptoms.
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