NEI Podcast

E278 - Re-release: Autism Spectrum Disorder and Comorbidities with Dr. Robyn Thom

Mar 25, 2026
Dr. Robyn Thom, Assistant Professor of Psychiatry at Harvard and clinician-researcher in autism care. She talks about how autism is diagnosed, core social and behavioral differences, and common co-occurring conditions like anxiety, ADHD, sleep problems, and agitation. Practical approaches for evaluating agitation, therapy and medication options, and research on syndromes like Williams are also discussed.
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ANECDOTE

Swim Lessons Sparked A Career In Autism

  • Robyn Thom first encountered ASD as a volunteer swim instructor teaching nonverbal communication strategies to children with autism.
  • That early hands-on work showed her how differently autistic children experience the world and inspired her later clinical focus at the Lurie Center.
INSIGHT

Autism Is Diagnosed By Behavior Not Tests

  • ASD is a behaviorally defined diagnosis without a definitive lab test, relying on clinical evaluation and symptom criteria.
  • Gold-standard tools like the ADOS and ADI-R exist for research but are often impractical for routine clinical practice.
INSIGHT

Two Core Domains Define The Autism Spectrum

  • Two core ASD domains are social communication differences and restricted repetitive patterns, and everyone must have both with widely varying severity.
  • Presentation ranges from socially motivated but awkward children to nonverbal individuals who resist social interaction.
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