
The Genius Life 124: Why We Get Fat, How to Fix Insulin Resistance, IGF-1 and Cancer | Benjamin Bikman, PhD
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Aug 19, 2020 Benjamin Bikman, PhD, discusses the relationship between fat cells and insulin resistance, the consequences of insulin resistance in chronic diseases, the link between IGF-1, insulin, and cancer, and optimizing protein consumption for growth.
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How A Paper Changed His Career
- Benjamin Bikman found a pivotal study showing fat cells release pro-inflammatory hormones, which changed his research focus.
- That discovery led him to study how fat-driven inflammation promotes insulin resistance and chronic disease.
Control Insulin Over Counting Calories
- Do prioritize foods that nourish but do not spike insulin; control carbohydrate quality and timing first.
- Keep insulin low to gain a metabolic advantage for higher resting energy expenditure and more fat burning.
Low Insulin Gives A Metabolic Advantage
- Lowering insulin raises resting metabolic rate and shifts fuel use toward fat and ketone production.
- Sustained low insulin can even lead to caloric 'wasting' via excreted ketones, aiding fat loss.

