The a16z Show

AI Just Gave You Superpowers — Now What?

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Mar 19, 2026
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INSIGHT

The AI Sandwich Reshapes Firms And Jobs

  • Catalini maps future work into directors, swarms of agents, and elite verifiers who check outputs with better tools.
  • He also adds meaning-makers, people who coordinate consensus, status, and cultural value where no single measurable right answer exists.
INSIGHT

Crypto Becomes Trust Infrastructure For AI

  • Crypto matters because AI lowers automation costs faster than verification costs, creating a trust gap across digital systems.
  • Catalini argues blockchains can anchor identity, provenance, payments, and chain of custody when human and agent activity become hard to distinguish.
INSIGHT

Human Edge Lives In The Exceptional Cases

  • What stays human for now is not average performance but the final judgment on exceptional cases across law, engineering, strategy, and art.
  • Catalini says seasoned people weight rare failures differently because they personally struggled through them, not just read examples in training data.
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