The Tim Ferriss Show

#851: Dr. Tommy Wood — How to Future-Proof Your Brain from Dementia

1466 snips
Jan 28, 2026
Dr. Tommy Wood, an associate professor in pediatrics and neuroscience who studies brain health across the lifespan. He covers newborn brain fuel and treatments for neonatal injury. He outlines acute concussion care and exercise-based recovery. He explores DHA, B vitamins, ketones, high-intensity and open-skill exercise, sleep, sensory health, supplements, and practical prevention strategies for dementia.
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Less Glucose = Brain 'Offline' Not Always 'Broken'

  • Reduced brain glucose uptake may reflect lower demand from inactive networks rather than an absolute supply failure.
  • Boosting cognitive and physical stimulation can restore metabolic demand and preserve function early on.

Mix Intensity And Open‑Skill Exercise

  • Do a mix: high‑intensity aerobic (lactate‑producing) sessions plus open‑skill, high‑coordination activities like dance or team sports.
  • Prioritize activities that produce lactate and require adaptation to maximize hippocampal and network benefits.

High‑Intensity Intervals Boost Hippocampus

  • Add 3×/week high‑intensity interval sessions (e.g., 4×4 min at 85–95% HRmax) for hippocampal growth if tolerated.
  • Short maximal sprints with long rests can also raise lactate and confer similar benefits.
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