Hello Hormones with Dr. Carrie Jones

Top 9 HRT Questions Every Woman Over 40 Is Asking

Jan 13, 2026
Confused about hormone therapy after 40? Learn the difference between natural progesterone and synthetic progestins. Discover safer alternatives to Prometrium for those with peanut allergies. Find out why topical progesterone creams may not protect your uterus. Uncover the true nature of estrogen patches and their contents. Explore the benefits of vaginal estrogen versus DHEA. Finally, understand how blood pressure fits into your hormone therapy decisions. Get the clarity you need to take control of your health!
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INSIGHT

Progesterone Vs Progestins

  • Progesterone is the body's natural hormone while progestins are synthetic and carry extra risks.
  • Micronized progesterone (OMP) improves oral absorption and is used in prescriptions like Prometrium.
ADVICE

Skip Prometrium With Peanut Allergy

  • Avoid Prometrium if you have a peanut allergy because it contains peanut oil.
  • Ask for oral micronized progesterone from a compounding pharmacy that omits peanut oil and fillers.
ADVICE

Topical Progesterone Doesn't Protect Uterus

  • Do not rely on topical progesterone cream to protect the uterus when using estrogen.
  • Use oral progesterone, a progestin IUD, or vaginal progesterone to prevent endometrial hyperplasia.
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