AFP: American Family Physician Podcast Episode 246 -- January 2026 -- Part 2 AFP: American Family Physician
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Jan 30, 2026 They cover treatments for endometriosis-related pain and limits of the evidence. A systems-based review of long-term complications in people with HIV and preventive monitoring. Use of GLP-1 agonists for adolescent obesity, with efficacy, access, and psychosocial concerns. When and how to stop antihypertensives in older adults. Evaluation and management of vertebral compression fractures. Buprenorphine dosing and retention in opioid use disorder.
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Hormonal Options Work Equally Well
- Multiple hormonal regimens reduce endometriosis pain but no single treatment is clearly superior.
- Trials had high risk of bias from unclear or absent masking which limits certainty.
Proactively Manage Cardiometabolic Health
- Screen and manage comorbid cardiometabolic conditions proactively in people with HIV.
- Use lipid panels at diagnosis, monitor glucose regularly, and treat according to standard guidelines.
Use Fasting Glucose, Not A1C
- Prefer fasting glucose over A1C when monitoring people with HIV starting or switching ART.
- Check baseline, recheck at 3–6 months, then annually if results are normal.