Dr Ford Brewer - PrevMed How I Use Nattokinase to Unclog Arteries - Ford Brewer MD MPH (PrevMed Health)
Feb 12, 2026
A deep dive into nattokinase origins and how people use it as a supplement. Discussion of a large 2022 trial showing dose-related reductions in arterial plaque and CIMT. Practical talk on dosing, measurement, and common mistakes. Safety, tolerance, and cautions about combining nattokinase with blood thinners are highlighted.
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How Nattokinase Affects Arteries
- Natto-derived nattokinase breaks down fibrin and can reduce blood 'stickiness' that contributes to plaque formation.
- It improves blood flow and creates a less inflamed arterial environment rather than literally scrubbing plaque off walls.
Patient Case: Dave's Plaque Journey
- Dave discovered soft arterial plaque on a CIMT scan and wanted to avoid statins while reversing plaque.
- After lifestyle changes and natokinase, Dr. Ford Brewer reports his plaque became more stable and less inflamed.
Dose-Response Shown In 2022 Trial
- A 2022 trial showed high-dose nattokinase produced large CIMT and plaque size improvements over a year.
- Only the high-dose group (≈10,800 FU/day) had major imaging changes, suggesting a strong dose-response.