Stop Damaging Your Liver with Professor Jacob George

Apr 16, 2026

Professor Jacob George, a leading clinician-investigator in hepatic medicine, shares why the liver matters far beyond alcohol. He explains how fatty liver develops, why routine tests miss silent disease, links to menopause and visceral fat, and how GLP-1s, diet, exercise and simple lifestyle changes can help the liver recover.

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ADVICE

Act Early Because Regeneration Stops With Cirrhosis

Healthy livers can regenerate; cirrhotic livers cannot recover their scarred architecture.
Jacob George notes surgeons can remove up to 70% of a normal liver and it regrows in weeks, but removal in cirrhosis causes failure.

INSIGHT

Fatty Liver Is A Metabolic Disease Not Just Alcohol

Fatty liver (MAFLD) is now the commonest liver disease driven by excess calories and metabolic dysfunction.
Jacob George describes fat infiltration (>5% of cells) causing oxidation, inflammation and progressive scarring.

ADVICE

Get Imaging Not Just Liver Bloods

If you have central (belly) fat or risk factors, get assessed with ultrasound or FibroScan since liver bloods can be normal.
Jacob George: 75% with fatty liver had normal AST/ALT; imaging specifically detects liver fat and fibrosis.

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In this must listen episode, we sit down with Australia's leading liver expert Professor Jacob George to talk about one of the body’s most important — and most overlooked — organs: the liver.

This miracle organ keeps us alive. It filters, processes, stores, regulates, and protects us, yet most of us know very little about it until something goes wrong.

Today that changes.

We discuss the basics of the liver along with why fatty liver is now so common, how it links to insulin resistance, visceral fat, menopause, and metabolic disease, and why liver disease can develop silently for years.

Professor George explains why liver health matters far beyond alcohol, and how it connects to blood sugar, cholesterol, hormones, inflammation, and long-term disease risk.

The good news? The liver can recover if we get in early.

We also cover the key tests to know, what can be missed, and the simple lifestyle changes that can help restore liver health and change your future trajectory.

Please share this episode with those who need to hear it.

If we want to live 120 healthy years we must make better choices for the liver.

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Guest Note

Professor Jacob George is a clinician investigator and Robert W. Storr Chair of Hepatic Medicine, University of Sydney (2007-) and Head, Department of Gastroenterology and Hepatology at Westmead Hospital (2006-). He has a proven record of delivering high impact research and teaching outcomes as well as demonstrating leadership at both national and international levels. His work spans basic and translational research on pre-cancerous liver diseases (fatty liver disease, viral hepatitis, liver fibrosis and cirrhosis) and liver cancer.