The Dr. Gundry Podcast Are You Vitamin B Deficient? (Symptoms Checklist Included) | EP 395.C
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Mar 20, 2026 A deep dive into why common B vitamin supplements sometimes fail and how genetic factors like the MTHFR mutation affect activation and absorption. Practical talk about intrinsic factor, why some B12 shots miss the mark, and why sublingual methyl B12 and methylfolate may work better for some people. Discussion of testing, managing adverse reactions, and links between B vitamins and mental health.
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Vitamin B Is A Family Not A Single Vitamin
- Vitamin B is a family of nutrients essential for energy production and brain function.
- Dr. Stephen Gundry emphasizes many people feel sluggish or foggy when B levels are low, linking B vitamins to vitality.
Half The Population May Not Methylate B Vitamins
- About 50% of people carry MTHFR mutations that impair converting B12 and folic acid into active methylated forms.
- Dr. Stephen Gundry explains lacking these enzymes means oral B12/folic acid may not become biologically active.
Use Sublingual Methyl B12 To Bypass Absorption Problems
- Do use sublingual methyl B12 and methylfolate to bypass poor intestinal absorption and intrinsic factor issues.
- Dr. Stephen Gundry recommends placing chewable or liquid methyl B12 under the tongue for direct absorption.