Physics World Weekly Podcast

Non-invasive pressure sensor could revolutionize how brain injuries are diagnosed

10 snips
Apr 10, 2025
Panicos Kyriacou, chief scientist at Crainio and professor of engineering, is pioneering a non-invasive optical sensor for measuring intracranial pressure, a critical factor in diagnosing brain injuries. He discusses the limitations of invasive methods and the urgent need for efficient, non-invasive alternatives. Kyriacou explains how the sensor uses light and machine learning to monitor blood flow in real-time, potentially revolutionizing brain injury assessments both in clinical settings and emergency situations.
Ask episode
AI Snips
Chapters
Transcript
Episode notes
INSIGHT

Light Reveals Pressure via Blood Flow

  • Optical sensor measures blood flow changes caused by brain vessel compression due to pressure.
  • Machine learning interprets these optical signals to estimate intracranial pressure non-invasively.
INSIGHT

PPG Captures Blood Volume Changes

  • Photoplethysmograph (PPG) captures blood volume changes in arteries during heartbeats.
  • Brain pressure compression alters artery elasticity, modifying the PPG signal to reflect intracranial pressure changes.
ANECDOTE

From Research to Clinical Trials

  • Cranio evolved from academic research to a startup with expert team and improved optical sensor technology.
  • Current device is approved by UK's MHRA and undergoing new clinical trials with leading hospitals and collaborators.
Get the Snipd Podcast app to discover more snips from this episode
Get the app