Ever since it opened in 1997, Cooper House has prided itself on offering a vibrant quality of life to people who are unable to live independently as a result of HIV/AIDS. The residential facility, located in St. Louis’ Central West End neighborhood, typically serves 36 individuals. But in 2020, that community dwindled to 27 people. We talk with Pat Plumley, chief program officer for Doorways, the nonprofit that oversees Cooper House, and medical director Dr. Jim Hinrichs, an infectious disease specialist.