The Body Pod

The Truth About Menopause and Hormones for Women Over 40 with Dr. Louise Newson

Sep 11, 2025
Dr. Louise Newson, a general practitioner and renowned hormone specialist, joins the discussion to revolutionize menopause care. She debunks myths about hormone therapy and highlights the essential roles of estrogen, progesterone, and testosterone in women's health. The conversation dives into the dangers of medical misinformation and emphasizes the need for individualized, evidence-based care. Also explored are how hormonal changes affect brain health, mood, and symptoms frequently mistaken for mental health issues. Empowering insights await women over 40!
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ADVICE

Prefer Transdermal Estradiol For Systemic Benefit

  • Choose estrogen route to match goals: transdermal (gel/patch) preserves estradiol and avoids first-pass liver metabolism.
  • If absorption varies, change patch/gel brand, site, or route until symptoms and blood levels improve.
INSIGHT

Local Vaginal Hormones Act Locally And Safely

  • Vaginal (local) estrogen and DHEA act locally with minimal systemic absorption and can be safe after breast cancer.
  • Vaginal therapies target vulva, vagina, urinary tract and pelvic floor effectively.
INSIGHT

Route Changes Progesterone Metabolism And Side Effects

  • Micronized oral progesterone undergoes liver metabolism producing metabolites that may cause side effects for some women.
  • Vaginal or rectal pessaries deliver progesterone via mucosa with fewer metabolite-related effects.
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