Everyday Oral Surgery Hematology Series: physiology, diagnostic tools, common coagulation pathology (with Drs. Andrew Jenzer and Maxwell Lloyd)
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Jan 13, 2025 Join Dr. Andrew Jenzer, an expert running a mock boards course for residents, and Dr. Maxwell Lloyd, a Boston-based hematologic oncologist specializing in breast cancer, as they explore blood and coagulation. They delve into the intricacies of hemostasis, the significance of lab interpretations, and common bleeding disorders like Von Willebrand's disease. Highlights include diagnostic tools for surgical safety, factors impacting coagulation tests, and the implications of key trials on treatment practices. It's a fascinating discussion that brings clarity to complex blood-related issues!
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Beware D-Dimer Limitations
- Treat elevated D-dimer with caution since many conditions elevate it non-specifically.
- Avoid using D-dimer after surgery to diagnose pulmonary embolism due to low specificity.
Use Mixing Study for Diagnosis
- Use mixing studies to differentiate factor deficiency from inhibitors in prolonged PT or PTT.
- Correction with normal plasma suggests deficiency; no correction suggests inhibitor.
Thromboelastography Revolutionizes Testing
- Thromboelastography (TEG) provides rapid, quantitative assessment of clot formation and breakdown.
- TEG aids targeted blood product therapy in complex coagulopathies like DIC.
