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Anti-Epileptic Drug Interactions
- Watch for drug interactions: carbamazepine, phenytoin, and phenobarbital induce enzymes reducing other drug effectiveness.
- Valproic acid inhibits enzymes, doubling lamotrigine levels; adjust doses carefully.
Choose Seizure Medications Wisely
- Use broad spectrum drugs like levetiracetam and valproic acid for generalized seizures.
- Avoid sodium channel blockers in generalized epilepsy as they can worsen myoclonus or absence seizures.
Important Anti-Seizure Drug Side Effects
- Know side effects: phenytoin causes gingival hyperplasia; carbamazepine causes hyponatremia.
- Topiramate causes kidney stones; levetiracetam may cause psychiatric side effects.