Mastering Nutrition Dmitry Kats, PhD: From Niatonin to Niacur
Flush Means Missed Colonic Action
- Kats concluded the flush is not anti-inflammatory but an undesired acidic 'spillover' when colonic receptor function is impaired.
- He emphasizes restoring colonic GPR109A engagement to obtain niacin's benefits without flushing.
GPR109A Links Butyrate To Immune Balance
- GPR109A signaling mediates butyrate's anti-inflammatory effects and promotes regulatory T-cell induction in the colon.
- Loss of this signaling increases susceptibility to chronic colitis and colorectal carcinogenesis.
Curcumin + Niacin Showed Strong Computational Hits
- Network and molecular studies identify niacin and curcumin as top hits against SARS-CoV-2 targets and inflammation pathways.
- Kats says these findings warrant further clinical investigation despite limited commercial incentives.
In this episode, I have Dr. Dmitry Kats, MPH, PhD. He has a PhD in epidemiology from the University of North Carolina at Chapel Hill. Many people have asked me what I think of his Niatonin protocol for COVID. And as you'll see in this interview that has since evolved into the Niacur protocol, which now has the dosing regimen of just niacin and curcumin, having abandoned the melatonin from the original protocol. You will find in this 3.5-hour conversation all about the justification for that protocol, how it evolved over time, where it came from, and you will get a really interesting look into the fascinating mind of Dr. Kats.
Important LinksFollow Dr. Kats on Telegram here: https://t.me/NiaCur
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Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.