The Joe Rogan Experience #459 - Dr. Rhonda Patrick
18 snips
Feb 20, 2014 
Dr. Rhonda Patrick discusses serotonin, DNA repair, gut microbiome, inflammation's impact on mental health, omega-3 benefits, fat consumption nuances, IGF-1's relationship to cancer, amino acids and growth hormone, caloric restriction's effect on aging, global events impact on physiology, deceptive supplement industry practices, debunking coffee mycotoxin myths, vitamin C in cancer treatment, defending stance on fracking, and importance of accuracy in health discussions.
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Measure And Maintain Vitamin D
- Test and maintain vitamin D levels rather than guessing dosage; aim for blood 25(OH)D > 30 ng/mL and possibly 40–60 ng/mL for lower all-cause mortality.
- Take vitamin D3 and adjust dose by body-fat and testing; Rhonda Patrick takes 4,000 IU/day and recommends testing to guide dosing.
Magnesium Enables DNA Repair
- Magnesium is essential for DNA repair enzymes, so deficiency impairs DNA repair and increases accumulated mutations over decades.
- Subclinical micronutrient shortfalls cause slow, insidious damage you won't notice until later-life diseases appear.
Demand Biomarkers In Nutrition Trials
- When evaluating supplementation trials require biomarker checks to show the intervention actually changed nutrient status.
- Ignore conclusions from trials that fail to raise participants' blood levels or measure compliance.