
Optimal Protein Podcast with Vanessa Spina Shocking New Research on Creatine & Collagen: What Women Need to Know - Benefits, Dosing & More!
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Dec 5, 2025 Discover the latest research on creatine and collagen – two powerhouse supplements for women! Learn how creatine boosts fat loss, enhances muscle tone, and even benefits cognitive function. Collagen’s surprising impact on biological age reveals its potential for skin rejuvenation and joint health. Plus, stacking these supplements could be a game-changer for healthy aging. Vanessa shares practical dosing tips and insights on their combined effects on longevity and overall wellness, making this an enlightening listen for women seeking optimal health.
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High-Dose Creatine Caused Painful Soreness
- Vanessa experimented with very high creatine doses (15–20 g) and felt painful shoulder soreness due to fluid shifts and low circulating volume.
- She returned to 5 g daily and emphasized increasing water intake when supplementing.
Verify Creatine Purity And Batch Testing
- Choose third-party tested, pure creatine that lists batch certificates and contains actual creatine monohydrate without fillers.
- Scan batch QR codes or verify lab reports to avoid low-dose or contaminated products.
Collagen Amino Acids Reduced Biological Age
- A 2025 NPJ Aging trial gave glycine:proline:hydroxyproline (3:1:1) and found average biological age reduced by 1.4 years in six months.
- Some participants saw reductions up to 8–12 years, suggesting targeted collagen amino acids signal fibroblasts to repair tissue.


