This Week in Virology

TWiV 1270: Clinical update with Dr. Daniel Griffin

Nov 15, 2025
In this episode, Dr. Daniel Griffin, an infectious disease clinician, shares vital insights from the ASTMH meeting. He discusses increasing H5N1 avian influenza outbreaks and the resurgence of measles, emphasizing vaccination’s importance. The conversation also covers early flu season trends, comparing high-dose and standard flu vaccine effectiveness, and recent RSV patterns. Dr. Griffin highlights the importance of staying vigilant about COVID-19 and outlines key public health actions, including the necessity of children's vaccinations to combat long COVID.
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ANECDOTE

Opening Defense Of Science

  • Daniel Griffin opened with an E.O. Wilson quote about science testing assumptions and defended scientific inquiry.
  • Vincent Racaniello echoed faith in science's role in explaining human conditions and health improvements.
ADVICE

Defend Science Publicly

  • Speak up in defense of science and support researchers facing legal or political attacks.
  • Recognize that attacks can cost careers and livelihoods and that collective voice matters.
ADVICE

Time Nirsevimab Doses For Infant Protection

  • Use nirsevimab to protect infants, noting strongest prevention occurs within six months of dosing.
  • Plan repeat dosing if protection beyond six to 11 months is required because effectiveness wanes after a year.
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