During the early weeks of the pandemic, Tim Hayward spent 14 days in a coma. He remembers this time vividly – his days and nights filled with strange, incandescent visions and hallucinations. That experience is something he would never choose to revisit but, around the world, large numbers of people are deliberately seeking out powerfully altered states.

In this ten-part series, Tim sets out to better understand a group of substances that induce altered states: psychedelics.

There’s been a surge of interest in their therapeutic potential for various mental health conditions - as well as a range of other clinical possibilities. As research around the world ramps up after years of taboo and prohibition he tries to get to grips with - or at least get a clearer sense of - how science, culture, politics and business might all interact in this changing psychedelic landscape, and what it all might mean.

He also explores what might be happening in the brain during a trip and whether, by studying psychedelics, we might uncover more about consciousness, imagination and even the mysteries of reality itself.

In this episode, Tim explores the many barriers to researching the potential therapeutic value and other potential applications of psychedelics. He assesses how other countries are weighing up and reacting to the current evidence, and asks if a tipping point may be looming in the UK.

Contributors: David Luke, psychiatrist and psychedelic researcher, University of Greenwich Lauren MacDonald, psychiatrist and psilocybin group facilitator Jo Neill, professor of psychopharmacology, University of Manchester and Chair of Trustees, Drug Science

Presenter: Tim Hayward Series Producer: Richard Ward Executive Producer: Rosamund Jones Editor: Kirsten Lass Written by Tim Hayward and Richard Ward Sound Design and Mixing: Richard Ward Researcher: Grace Revill Production Executive: Lisa Lipman Commissioning Editor: Daniel Clarke A Loftus Media production for BBC Radio 4

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