In this episode of the Oncology Brothers podcast, we dived into the key takeaways from ESMO 2025, focusing on gastrointestinal (GI) malignancies. Join us as we welcomed Dr. Rachna Shroff, a GI medical oncologist from the University of Arizona, to discuss the latest studies and their implications for clinical practice.
Episode Highlighted:
• ctDNA in Colorectal Cancer: DYNAMIC-III and PEGASUS studies, examining the evolving role of ctDNA as a prognostic and potential predictive tool in early-stage colon cancer.
• STELLAR-303: Learn about the promising results of immunotherapy in refractory MSI-stable colorectal cancer and the associated toxicities.
• MATTERHORN: Updated data on durvalumab with FLOT in the perioperative setting is changing the standard of care for upper GI malignancies.
• FORTITUDE-101 Study: FGFR2b target in metastatic gastric and GE junction adenocarcinoma.
Tune in for an insightful discussion that highlights the latest advancements in oncology and their potential impact on patient care.
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Don't forget to check out our previous episodes for more insights on conference highlights, recent approvals, and treatment algorithms.
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