Peptides like BPC‑157 and evidence gaps

I’ve known Dr. Spencer Nadolsky for well over a decade and he’s been my go to resource when it comes to GLP-1’s and any peptides that help with weight loss, metabolic health, health and performance in general. It was great to catch up and get the truth about GLP-1’s from an expert that is helping clients in the real world, daily.

Dr. Spencer Nadolsky, a board-certified family and obesity medicine physician and a leading voice in metabolic health. Known as 'The Doc Who Lifts,' Spencer specializes in the intersection of medicine and lifestyle, helping patients achieve sustainable weight loss and improved heart health through evidence-based nutrition and exercise. He currently serves as the Medical Director at WeightWatchers and is the co-host of the Docs Who Lift podcast. With a background as a former D1 wrestler, he brings a unique perspective on using strength training and modern medicine to treat obesity.

IN THIS EPISODE YOU’LL LEARN: 

=> History of GLP-1’s from diabetes to weight management and what FDA recommends.

=> What is the recommended criteria for using GLP-1’s and what does Dr. Nadolsky recommend and which patients does he use it with, and why.

=> Why Spencer is ok with people looking to lose “the last 10-20 lbs” using GLP-1’s but draws the line at ______.

=> Do GLP-1’s truly affect muscle loss and lowering of bone density, or are those side effects of extreme dieting, lack of strength training, and not enough calories and protein.

=> How small is the percentage of people that can lose weight and keep it off for good, and why judgement of people taking GLP-1’s is hurting more than helping.

=> The reason why resistance training is a MUST on a diet or on GLP-1’s; these stats will blow you away. 

=> How our environment has changed dramatically and is aligned with the rise in obesity; that is not going to change but here is the solution.

=> We discuss the psychology of exercise, diet, and drugs; and what makes someone “undisciplined” (and the misconceptions of it). 

=> What does Dr. Nadolsky recommend to every person that gets on GLP-1’s for best results and long term health. 

=> Do some people need to lose weight and feel better BEFORE they start lifting weights.

=> The misconception of doctors being “Pharma shills” and what the behind the scenes really look like.

=> Why some people have gastrointestinal issues while on GLP-1’s, and what you MUST do to avoid those issues. 

=> What happens when you “stress test” drinking alcohol while starting GLP-1’s. 

=> Lower fat meals, higher fiber, moderate protein, is a good starting point for people beginning to take GLP-1’s.

=> Should you continue to stay on GLP-1’s, get off at a certain point in time, or lower the dose; answered in detail. 

=> The cost of GLP-1’s and how they can be barrier for people staying on them.

=> How dosing the drug is very important in getting best results; Dr. Nadolsky explains how to dose it and if you even should dose it up. 

=> Why you MUST have appetite to get enough calories in to support your goals and life (if you are lifting, running, etc). 

=> Zepbound “quick pens” and how they’re allowing better micro and precision dosing of GLP-1’s.

=> What are the studies behind peptides such as BPC-157, CJC-1295/Ipamorelin, TB-500, Thymosing Alpha, and more.

=> Is Retatrutide a “miracle drug” or is it just hype.  

=> What is the best way to get peptides and the dangers of getting it from non FDA approved compound pharmacies. 

LINKS & RESOURCES:

Dr. Spencer Nadolsky website  https://drspencer.com/

Docs Who Lift Podcast https://podcasts.apple.com/us/podcast/docs-who-lift/id1611961208

Dr. Spencer Nadolsky YouTube https://www.youtube.com/@drnadolsky/videos

Dr. Spencer Nadolsky Instagram https://www.instagram.com/drnadolsky/

Vineyard  https://joinvineyard.com/

Super Coach Mentorship https://lukahocevar.com/super-coach-mentorship/

Luka Hocevar YouTube Channel https://www.youtube.com/@Luka-Hocevar/videos