Could an enzyme deficiency explain why you have food intolerances causing bloating, loose bowels, reflux, brain fog, joint pain, skin issues, and more? Namely, sucrase isomaltase.

This enzyme, known as the sucrase-isomaltase enzyme, may be deficient in many people dealing with chronic GI issues. One study found that 8% of people were at an increased genetic risk for this deficiency (https://jpedres.org/articles/frequency-of-congenital-sucrase-isomaltase-deficiency-by-whole-exome-sequencing-is-it-really-rare/doi/jpr.galenos.2024.65625?utm_). Another study found that 25% with chronic GI symptoms had issues breaking down sucrose (https://pubmed.ncbi.nlm.nih.gov/36304608/).

Thankfully, a diet exists for this which has been studied and shown to be very effective. In fact, it's been shown to be as or even more effective than some of the best diets we currently have for improving gut health – therefore maybe the best diet for gut health?

Let's break down what this enzyme deficiency is, what the diet is, SSRD, and how this diet applies and can be helpful even for those with underlying fungal or bacterial overgrowth and leaky gut.

📖 Free Low Sucrose Diet Guide: https://drruscio.com/guides/get-low-sucrose-starch-diet-guide/ (16:19)

💊 Elemental Heal: https://store.drruscio.com/products/elemental-heal-whey-free (18:50)

💊 Digestive Enzyme with HCL: (19:40)

https://store.drruscio.com/products/digestive-enzyme-with-hcl?variant=5245788684325

💊 Intoleran Starchway Digestive Enzymes: (19:52):

https://www.amazon.com/Intoleran-Starchway-Sucrose-Intolerance-Digestion/dp/B0B7BKJ6Y7?utm_=undefined&th=1

✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/

👇 Watch more videos like this 👇

➡️ Why You Have Abdominal Bloating & Pain – And How to Fix It:

https://www.youtube.com/watch?v=mZL3fWbkg8A

➡️ The Top 5 Gut Treatments For IBS, Bloating & Acid Reflux in 2025:

https://www.youtube.com/watch?v=W34IPkhuXyc

➡️ Constipation Fixes That Actually Work (Root-Cause Approach):

https://www.youtube.com/watch?v=g8kYTupkPQc

➡️ The 4 MOST Effective Leaky Gut Treatments:

https://www.youtube.com/watch?v=MW1ezm3d0JQ

Subscribe: https://www.youtube.com/@DrRuscioDC?sub_confirmation=1

And if you have any questions or topics you would like covered in the future, let me know in the comments!

👇Read these next 👇

➡️ How to Heal Your Gut Naturally: A Clinician's Guide:

https://drruscio.com/how-to-heal-your-gut-naturally/

➡️ 8 Best Microbiome Supplements for a Happier, Healthier Gut:

https://drruscio.com/best-microbiome-supplements/

📌Timestamps

00:00 Intro

01:18 Enzyme Deficiency: CSID

03:46 Study Setup

06:27 Study Results

08:19 Why the SSRD Diet Might be Best

11:22 Microbiota Impacts

12:40 Testing

13:35 SSRD Diet Guidelines

18:41 Supplements

20:01 Key Points

Featured Studies

📉Frequency of Congenital Sucrase-Isomaltase Deficiency by Whole Exome Sequencing: Is It Really Rare?

https://jpedres.org/articles/frequency-of-congenital-sucrase-isomaltase-deficiency-by-whole-exome-sequencing-is-it-really-rare/doi/jpr.galenos.2024.65625?utm_

📉The Relationship between Gastrointestinal Health, Micronutrient Concentrations, and Autoimmunity: A Focus on the Thyroid: https://pubmed.ncbi.nlm.nih.gov/36079838/

📉Sucrose intolerance in adults with common functional gastrointestinal symptoms:

https://pubmed.ncbi.nlm.nih.gov/36304608/

📉A Starch- and Sucrose-Reduced Diet Has Similar Efficiency as Low FODMAP in IBS:

https://pubmed.ncbi.nlm.nih.gov/39275354/

📉The Relationship between Gastrointestinal Health, Micronutrient Concentrations, and Autoimmunity: A Focus on the Thyroid: https://pubmed.ncbi.nlm.nih.gov/36079838/

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.

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