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Leucine + Metformin In Phase II Human Trials | Prof Michael Zemel Ep 3

Modern Healthspan

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Introduction

NSO 100 was simply a combination of leucine and low dose metformin. We showed in animal studies that leucine-metformin were highly synergistic. Less well known is metformin does have a little bit of an effect on CERT1 as a direct effect, so there's cross talk between the enzymes.

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