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Basic Science | General and Regional Anesthesia in Orthopaedics

The Orthobullets Podcast

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What Is the Correct Antidote for Hyperthermia?

Morris at all compared bipolar versus standard monopolar electrochordery and anterior total hip arthroplasty. They found similar transfusion rates and postoperative drop in hemoglobin between groups, although the bipolar group had an average of 12.5cc's more blood loss. The correct answer to this question is 2, dantraline. Dantraline is the antidote for malignant hyperthermia. It causes a hypercatabolic state with increased skeletal muscle metabolism,. Rapid oxygen depletion, increased carbon dioxide concentration, and increased body temperature leading to circulatory collapse and death.

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