43. The Soft (w/ Laura Tripaldi)
Disintegrator
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We're joined by Laura Tripaldi: material scientist, writer, and researcher at the Center for AI and Culture at NYU Shanghai. You probably know her from Parallel Minds: Discovering the Intelligence of Materials (Urbanomic, 2022), an essay in book form that became a phenomenon in theory and art circles.
Tripaldi's work challenges one of the strongest contentions within the philosophy computation: that intelligence is substrate-indifferent, that it can scale and migrate independent of what carries it. She argues the opposite, that you cannot separate intelligence from the materials through which it is conveyed.
This becomes experimentally clear in her recent essay Substrates Unbound (Antikythera, 2025), where she tracks biocomputing systems like DishBrain — living neuronal cultures interfaced with silicon chips that don't execute pre-given code but reorganize, learn, and adapt. Mouse neurons and human neurons perform differently under the same training conditions. This reframes a central question of the moment: not 'can we scale intelligence,' but which matter are we asking to think, under what energy regime, and at what cost?
References:
Tripaldi's work challenges one of the strongest contentions within the philosophy computation: that intelligence is substrate-indifferent, that it can scale and migrate independent of what carries it. She argues the opposite, that you cannot separate intelligence from the materials through which it is conveyed.
This becomes experimentally clear in her recent essay Substrates Unbound (Antikythera, 2025), where she tracks biocomputing systems like DishBrain — living neuronal cultures interfaced with silicon chips that don't execute pre-given code but reorganize, learn, and adapt. Mouse neurons and human neurons perform differently under the same training conditions. This reframes a central question of the moment: not 'can we scale intelligence,' but which matter are we asking to think, under what energy regime, and at what cost?
References:
- Tripaldi, Laura. Parallel Minds: Discovering the Intelligence of Materials (Urbanomic, 2022).
- Tripaldi, Laura. "Substrates Unbound" (Antikythera, 2025).
- Tripaldi, Laura. Soft Futures (newsletter, Substack).
- Haraway, Donna. A Cyborg Manifesto (1985).
- Parisi, Luciana. Abstract Sex: Philosophy, Biotechnology and the Mutations of Desire (Continuum, 2004) — source of the concept of hyper nature.
- Hui, Yuk. The Question Concerning Technology in China (Urbanomic, 2016) — source of the concept of cosmotechnics.
- Barad, Karen. Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning (Duke, 2007) — onto-epistemology and intra-action.
- Irigaray, Luce — referenced as an influence on Tripaldi's feminist materialism.
- Pasquinelli, Matteo. The Eye of the Master: A Social History of Artificial Intelligence (Verso, 2023) — discussed in relation to technology as captured labor; Tripaldi pushes back via the history of automata.
- Laschi, Cecilia. Soft Robotics Lab, National University of Singapore — pioneer of octopus-inspired soft robotics.
- Hookway, Branden. Interface (MIT Press, 2014).
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