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Antibiotic Duration for Febrile UTI in Males, Lower GI Bleeding Guidelines, Intravenous Contrast in Patients with Acute Kidney Injury

Last Week in Medicine

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Antibiotics and Non-Inferiority Trials

Non-inferiority trials are unique to medicine, and we're just going to keep seeing them more and more. The FDA has defined an acceptable margin of 10%, which I don't know if that's arbitrary or not. They powered their study to have 80% power, and their non-in feriority margin was 10%.

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