Evidence Strength and Trial Limitations

MDMA psychotherapy was approved in Australia three years ago. Who's using it and what do we know about treatment side effects?

Vaccine reminders can help nudge people back on track, but how the message is framed matters.

A new review of screen use and sleep in young people finds no link between the amount of use and sleep quality or duration.

And a different way of looking at mental health outcomes - whether digital tools can help us forecast someone's future needs and provide better, more personalised care.

References:

• Within-Person Association Between Daily Screen Use and Sleep in Youth
• Acetaminophen (Paracetamol) or Opioid Analgesia Added to Ibuprofen for Children’s Musculoskeletal Injury
• Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial
• Side-effects of MDMA-assisted psychotherapy: a systematic review and meta-analysis
• Experiences of Australian clinicians, researchers, and patients with MDMA-assisted psychotherapy for post-traumatic stress disorder: A framework-guided qualitative analysis
• The AuTOMATIC trial: a multicentre digitally-automated, Bayesian, adaptive, parallel, factorial randomised controlled trial of SMS reminders for childhood vaccination
• The necessity of digital measurement-based care for navigating complexity in youth mental health
• Dynamic learning of individual-level suicidal ideation trajectories to enhance mental health care