
Basic Science⎪Fracture Healing
The Orthobullets Podcast
00:00
Bone Growth During Primary Bone Healing
The correct answer is two, change in length over original length of an object due to an external force. Granulation tissue can withstand higher strain which stabilizes the mechanical environment and forms a scaffold on which cartilage and bone eventually form. Osteoblast synthesis and proliferation is stimulated at uniaxial strain of between 0.3% and 2.8%. It is known that limited inter fragmentary movement of 0.2mm to 1mm is optimal for fracture healing,. resulting in promotion of callus and increase in rigidity. Excessive motion on the other hand prolongs fracture healing. Researchers have identified that tissue strain of 2% is suitable for primary bone healing; secondary bone
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