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TWiP #5 - The nurse cell

This Week in Parasitism

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Exploring Angiogenesis and Parasitic Manipulation

This chapter delves into the process of angiogenesis induced by vascular endothelial growth factor (VEGF) secreted by muscle cells, highlighting how parasites manipulate hosts by influencing protein production. It discusses the role of metalloproteases in blood vessel formation and explores a unique sugar connected to worm proteins and their impact on angiogenesis. The chapter also examines the construction of 'nurse cells' by parasites, compares different Trichinella species, and looks at potential medical applications for understanding sinusoid formation.

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