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Mind Control with Lasers: Optical Recording Part II

Neurotech Pub

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The Importance of Calcium Imaging in Neuroscience

There is a direct relationship between the calcium and the spikes, but it depends on the amount of indicator in the cell. So if you want to image more and more neurons, you've got to go over a larger and larger field of you and get less good information about each cell. And that's what they quantified pretty well in this allan institute paper. They quantified, sort of, as you zoom out and you get more neurons, what effect does that have on how well you can read out the spikes? We'd like to know precisely how many spikes occurred in all those nerons.

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