Antidepressants for gut pain

Exciting news - pre-order my debut book 

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I've never spoken publicly about my polyposis syndrome. About the bowel obstruction. About spending years doing everything right. The diet, the supplements, the appointments, and still ending up in hospital. I share it in this episode, because Will said something that made it impossible not to. Healing, he told me, didn't really begin until he fixed his relationship with his father. Not his diet. His dad.

This week on Live Well Be Well, I sat down again with the brilliant Dr. Will Bulsiewicz, gastroenterologist, gut health researcher, and author of the brand new Plant Power Plus, for a conversation that starts in the gut and ends somewhere far more human. Will has this extraordinary ability to make the most complex science feel personal and urgent, and this one,  our third conversation together, might be the most honest we've ever been.

Here's What We Dive Into:

- How half the population has normalised a damaged gut microbiome without ever realising it.

- Why your symptoms, health history, and poop tell a more complete story than any expensive gut test.

- Why fiber is the longevity nutrient and how to introduce it without the bloating and pain.

- How colorectal cancer became the leading killer of millennials and Gen Z, and the screening 

steps that can protect you.

- What one evening of drinking does to your gut lining within the hour.

- Why unresolved trauma, stress, and your closest relationships may be the missing piece in your gut healing.

Love,

Sarah Ann 💛

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***

The Great British Veg Out

How to support your gut, energy, and hormones by eating more — not less.

👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out

Reset Your Health

If your body feels off after stress, travel, or burnout — this is where to start.

👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days

👉 Practical beats perfect.

Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.

https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve

👉 If this resonates, you can join the thousands who read

The Compassionate Cure each week. https://sarahmacklin.substack.com/

***

If You Enjoyed This Episode, You Might Also Like:

Akkermansia, Cancer & GLP-1: How Your Gut Microbiome Shapes Immunity & the Brain | Dr William Lihttps://youtu.be/yZDzsfNjG_M

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Science Simplified, Health Humanised.

Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact.

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(00:00) Intro

(00:03:49) How to Know If Your Gut Is Healthy

(00:06:25) What Your Poop Says About Your Health

(00:08:02) Signs You're Constipated (And Don't Know It)

(00:13:00) Why Antidepressants Are Prescribed for Gut Problems

(00:18:39) How to Fix Chronic Constipation

(00:24:32)How to Choose a Fiber Supplement

(00:30:56) Akkermansia: The Gut Bacteria That Fights Cancer

(00:41:28) How Stress Destroys Your Gut Microbiome

(00:46:38) Polyps, Bowel Obstruction & Why I Changed My Diet

(00:58:13) How to Add Fiber Without Bloating or Pain

(01:05:49) Why High Protein Diets Harm Your Gut

(01:15:55) How to Repair Your Gut Lining in 3–5 Days

(01:26:57) Why Hangovers Are a Gut Problem (Not Just Alcohol)

(01:41:54) Why Diet Alone Won't Heal Your Gut

(01:51:13) What It Means to Have an Authentic Self