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Episode 130: Quality of Life, Patient-Reported Outcomes, and Clinical Trials

Healthcare Unfiltered

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The Three Key Ways That PROs Can Inform Clinical Trials

Each trial needs a hypothesis about the quality of life outcome. So PROs are increasingly used as a primary study endpoint, which I think is fantastic. We just published a paper recently in JNCI that spelled out the three key ways that this can inform clinical trials. The second class of outcomes is where you're trying to describe the harms of treatments so that you can balance those against the benefit. And the third class is when it actually tips the balance.

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