Role of Vitamin B6 in Neurotransmission

Are your vitamins causing nerve pain? Discover the vitamins that worsen nerve pain and peripheral neuropathy, why certain nerve pain vitamins make matters worse, and what you can do to fix it.

0:00 Introduction: Vitamins that worsen nerve pain

0:12 Vitamin B6

1:59 Vitamin B12

4:17 Vitamin B1 deficiency and peripheral neuropathy

4:35 Nerve pain vitamins

5:39 Alpha-lipoic acid for peripheral neuropathy

6:41 Avoiding vitamins that worsen nerve pain

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If it seems that your vitamins are making nerve pain worse, the solution might be simple. Vitamin B6 is vital in neurotransmission, but must be converted to its active form through the liver. Unconverted vitamin B6 can accumulate in the body and affect the nervous system if your liver is sluggish, if you don't have enough bile, or if you’re low in glutathione. Inflammation, high blood sugar, and low magnesium can also inhibit your ability to make this conversion.

Most vitamin B12 supplements contain cyanocobalamin, which is useless unless converted into the active form, methylcobalamin.

Vitamin B1 is vital in supporting the mitochondria and the myelin sheath. Low vitamin B1 is a common cause of peripheral neuropathy.

Vitamins B1, B6, and B12 are water-soluble vitamins, so they can’t easily penetrate the brain and myelin sheath. Benfotiamine is a fat-soluble form of vitamin B1 that can penetrate the myelin sheath to help reverse peripheral neuropathy.

Alpha-lipoic acid is a powerful antioxidant that can help with peripheral neuropathy, support mitochondrial function, and improve insulin sensitivity.

Key takeaways:

1. Use the right forms of vitamin B1, vitamin B6, and vitamin B12

2. Don’t go over 50 mg per day

3. Ensure you have enough bile

4. Consume fermented foods

5. Make sure your insulin is balanced

6. Don’t forget about alpha-lipoic acid

Dr. Eric Berg DC Bio:

Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.

Disclaimer:

Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.